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Do you want to have both the compute power of GPU’s and the programming convenience of Python numpy? Gnumpy + Cudamat will bring you that.
Gnumpy is a simple Python module that interfaces in a way almost identical to numpy, but does its computations on your computer’s GPU. See this example, training an RBM using Gnumpy.
Gnumpy runs on top of, and therefore requires, the excellent cudamat library, written by Vlad Mnih.
Gnumpy can run in simulation mode: everything happens on the CPU, but the interface is the same. This can be helpful if you like to write your programs on your GPU-less laptop before running them on a GPU-equipped machine. It also allows you to easily test what performance gain you get from using a GPU. The simulation mode requires npmat, written by Ilya Sutskever.
Gnumpy is licensed with a BSD-style license (i.e. it’s completely free to use for everyone, also as a component in commercial software), with one added note: if you use it for scientific work that gets published, you must include reference to the Gnumpy tech report in your publication. For details of the license, see the top of gnumpy.py.
See also this presentation by Xavier Arrufat, introducing numpy at the Python for Data Analysis meetup in Barcelona, 2013.